MicroRNAs Reprogram Normal Fibroblasts into Cancer-Associated Fibroblasts in Ovarian Cancer
نویسندگان
چکیده
منابع مشابه
MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer.
UNLABELLED Cancer-associated fibroblasts (CAF) are a major constituent of the tumor stroma, but little is known about how cancer cells transform normal fibroblasts into CAFs. microRNAs (miRNA) are small noncoding RNA molecules that negatively regulate gene expression at a posttranscriptional level. Although it is clearly established that miRNAs are deregulated in human cancers, it is not known ...
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ژورنال
عنوان ژورنال: Cancer Discovery
سال: 2012
ISSN: 2159-8274,2159-8290
DOI: 10.1158/2159-8290.cd-12-0206